The Best Glucosamine for Dogs

Glucosamine is a substance that occurs naturally in your dog’s body and it’s mostly found in healthy cartilage – a spongy material that acts as a cushion between joints. Cartilage cells are always turning over, and when the tissue is damaged, the joint becomes inflamed, which leads to pain and stiffness. Glucosamine helps form and repair body tissues such as cartilage. However, as dogs age, the natural production of glucosamine in their body slows down, and consequently, the repairing of cells becomes slower, which leads to arthritis and impaired mobility. Glucosamine supplements are used to alleviate the pain caused by damaged cartilage and to boost the repair of these cells.

We looked over dozens of glucosamine supplements for dogs aiming to find high-quality products which have many positive reviews and recommendations. We took into account the package counts, Amazon ratings, price, and what people had to say about them in their reviews. We picked out top 5 of the best-rated glucosamine supplements you can buy for your four-legged friend. If your dog has skin issues such as allergies or itching, you can take a look at our list of the best dog skin and coat supplements.

Top pick
Nutramax Cosequin DS Plus with MSM Chewable Tablets

Nutramax Cosequin gets your aging dog back on their feet with its powerful formula that improves motion and reduces pain.

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After careful consideration, we identified Nutramax Cosequin DS Plus with MSM Chewable Tablets as a top choice. It contains a mixture of ingredients that help to protect your dog’s joints and support healthy cartilage production.

The 5 Top-Rated Glucosamine for Dogs

Editor's PicksBrandRating
Best OverallNutramax Cosequin DS Plus with MSM Chewable Tablets4.7
Runner UpDoggie Dailies Glucosamine for Dogs4.4
Best Budget BuyProSense Glucosamine for Dogs4.4
Best Glucosamine Chews for DogsZesty Paws Senior Advanced Glucosamine for Dogs4.7
Best Liquid Glucosamine for DogsTerraMax Pro Best Hip and Joint Supplement for Dogs
4.5

*Ratings are from Amazon at the time of publication and can change. 

Our Top Pick: Nutramax Cosequin DS Plus with MSM Chewable Tablets

Nutramax Cosequin DS Plus with MSM Chewable Tablets contains chondroitin sulfate, another natural substance, which helps cartilage retain water. It also contains MSM (methylsulphynolmethane), a natural sulfur compound that helps improve joint flexibility and reduce pain and inflammation. This combination of ingredients can be extremely beneficial for your dog’s joint health. According to the reviews, this supplement works great with dogs that suffer from arthritis or have other joint or hip problems as it makes them move around much easier.

Nutramax Cosequin is suitable for dogs of all ages, sizes, and activity levels, but you should consult the vet for the right dosage. The recommended initial administration period is 4 to 6 weeks, although some dogs may respond to the supplement sooner. The product comes in the form of 132 chewable tablets. It’s available at the price of $35.

Nutramax Cosequin DS Plus with MSM Chewable Tablets Key Features:

  • Contains chondroitin sulfate and MSM that help improve joint function
  • Helps dogs that have arthritis or other joint/hip problems
  • Suitable for dogs of all ages, sizes, and activity levels
  • The recommended initial administration period is 4 to 6 weeks
  • 132 chewable tablets

Our Runner-Up Pick: Doggie Dailies Glucosamine for Dogs

Runner Up
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Doggie Dailies Glucosamine for Dogs

Doggie Dailies offer a blend of ingredients that help reduce inflammation, repair cartilage, and protect your pet’s skin and coat.

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$49.99 USD

Doggie Dailies Glucosamine for Dogs is a joint supplement that provides vitamins, minerals, essential enzymes, and nutrients your dog needs for natural energy and strength. It’s intended to relieve your dog of pain caused by aging, hip dysplasia, and arthritis. It features a blend of ingredients that help improve mobility, including glucosamine, chondroitin, MSM, coenzyme q10, and hyaluronic acid. Coenzyme Q10 supports the heart and kidneys and increases natural energy levels. Hyaluronic acid increases the joint fluid’s thickness, which provides additional cushioning for the joint. The product also contains Omega 3 & 6, Vitamin C & E, and salmon oil to boost skin and coat health.

This glucosamine supplement is suitable for dogs that are at least 6 months old. It features 225 soft chews with a chicken flavor. Many of the reviewers mention that their dogs like the taste and that they noticed a significant improvement in their pets’ mobility. The product is made in the USA in FDA-registered factory. It’s available at the price of $34.

Doggie Dailies Glucosamine for Dogs Key Features:

  • Formulated to relieve your dog of pain caused by aging, hip dysplasia, and arthritis
  • Glucosamine, chondroitin, MSM, coenzyme q10, and hyaluronic acid improve mobility and boost energy levels
  • Omega 3 & 6, Vitamin C & E, and salmon oil help support healthy skin and coat
  • 225 soft chews with a chicken flavor
  • Suitable for dogs that are 6 months and older
  • Made in the USA
  • Money-back guarantee

Best Budget Pick: ProSense Glucosamine for Dogs

Best for Budget
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ProSense Glucosamine for Dogs

ProSense Glucosamine supports joint function and cartilage health and it includes Vitamin C to promote collagen growth.

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$25.99 USD

ProSense Glucosamine for Dogs helps with joint and hip problems. It improves your dog’s mobility and flexibility and, combined with Vitamin C, it promotes collagen growth. For $18 you get a pack of 120 tablets your dog can chew easily. According to the reviews, the supplement is particularly beneficial for older and overweight dogs that have difficulties walking. 

It’s recommended to give ProSense Glucosamine to your dog during or after a meal to avoid potential gastrointestinal upsets. The initial administration period lasts between 4 and 6 weeks. It’s best to consult the vet on recommended daily dosage. 

ProSense Glucosamine for Dogs Key Features

  • Glucosamine and MSM improve your dog’s mobility and flexibility 
  • Vitamin C promotes collagen growth
  • Beneficial for older and overweight dogs
  • Pack of 120 chewable tablets
  • Should be administered during or after a meal
  • Initial administration period lasts between 4 and 6 weeks

Best Glucosamine Chews for Dogs: Zesty Paws Senior Advanced Glucosamine for Dogs

Best Glucosamine Chews for Dogs
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Zesty Paws Senior Advanced Glucosamine for Dogs

Zesty Paws Glucosamine for senior dogs is formulated with curcumin, green-lipped mussel and hyaluronic acid to promote flexibility, strength, and comfort.

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Zesty Paws Senior Advanced Glucosamine for Dogs is formulated with a mixture of ingredients that increase flexibility, range of motion, and comfort in aging dogs. These chew treats contain glucosamine, chondroitin sulfate, and MSM, which are known to have a positive effect on joint pain and stiffness. Additionally, the supplement contains turmeric curcumin, black pepper, green-lipped mussel, hyaluronic acid, Vitamin C, Vitamin E, and hemp extract, which all play a significant part in improving your dog’s mobility and enabling them to walk around pain-free in their senior years. 

Zesty Paws glucosamine can be used by dogs of all breeds and sizes. These chew treats come with a chicken flavor and a soft texture so that aging dogs can enjoy them. There are 90 chews per package and you can get it at the price of $35. 

Zesty Paws Senior Advanced Glucosamine for Dogs Key Features

  • Supports hip and joint health in senior dogs
  • Features curcumin and black pepper
  • Contains green-lipped mussel and hyaluronic acid
  • Chicken flavor
  • 90 chew treats per package

Best Liquid Glucosamine for Dogs: TerraMax Pro Best Hip and Joint Supplement for Dogs

Best Liquid Glucosamine for Dogs
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TerraMax Pro Best Hip and Joint Supplement for Dogs

TerraMax Pro supplement features a liquid formula that helps maintain the resiliency of joints and connective tissues using human-grade ingredients.

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$69.95 USD

TerraMax Pro Best Hip and Joint Supplement for Dogs is formulated with glucosamine, chondroitin, and MSM for maximum joint support and healthy cartilage. It also contains hyaluronic acid, which provides thicker cushioning for the joint, and consequently, reduce pain and stiffness. This supplement is made of human-grade ingredients and it doesn’t contain sugar, salt, wheat, milk or soy derivatives. 

According to many reviews, dogs don’t mind the taste of this supplement and the owners noticed improvement in their pets’ mobility after a short period of time, most often after 6 weeks of use. TerraMax glucosamine is easy to administer, you simply pour the recommended dosage to your dog’s food or drinking water. You should always consult the vet about the recommended dosage. You can get this product for $40. 

TerraMax Pro Best Hip and Joint Supplement for Dogs Key Features

  • Formulated with glucosamine, chondroitin, and MSM
  • Features hyaluronic acid
  • Made of human-grade ingredients
  • No sugar, salt, wheat, milk or soy derivatives
  • 32 oz.

Who Should Buy Glucosamine for Dogs 

It’s hard for dog owners to see their pets struggle with mobility as they get older. Deterioration of joints occurs naturally as dogs age, but that doesn’t mean that you can’t do anything to make their senior years easier and more comfortable. Glucosamine supplements can be extremely beneficial for dogs as they can help them perform daily activities such as going up and down the stairs, on and off the furniture or simply going out for a walk. Aging dogs with hip and joint problems may find it difficult to do all these things, but glucosamine can help reduce the pain during daily exercise.

Glucosamine helps with conditions such as arthritis and hip dysplasia, but it can also be given to healthy dogs as means of prevention. There are certain dog breeds that are more likely to have joint problems than others, such as Germen Shepherds and Golden Retrievers, so including supplements in their diet as soon as they are old enough to take them can reduce the impact of joint issues as they get older. However, It’s important to always consult the vet before you decide to give your dog any type of medication or a supplement. The vet will also be able to give you advice on the type of supplementation your dog needs as well as on the recommended dosage. For most glucosamine supplements, the initial administration period is 4 to 6 weeks, although the vets claim that you should be able to see improvement after your dog has been using the supplement for about 3 months. 

Top pick
Nutramax Cosequin DS Plus with MSM Chewable Tablets

Nutramax Cosequin gets your aging dog back on their feet with its powerful formula that improves motion and reduces pain.

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Important Features to Consider

A proper glucosamine supplement should do several things well. Here’s what to consider when selecting a glucosamine supplement for your pet: 

  • Ingredients. Naturally, the ingredients in the glucosamine supplements are the ones that improve the condition of the joints, so the type and the amount of ingredients is very important. Most glucosamine supplements come in the combination with chondroitin sulfate and MSM, which are known to help with joint pain and stiffness. There should also be a sufficient amount of these ingredients in the product for it to be able to have any kind of effect. Glucosamine supplements can also contain vitamins, various oils, fatty acids, or yeast. If your dog is allergic to any ingredient, you need to pay attention whether the product includes it. 
  • Safety. It’s advisable to look for product’s certifications and recommendations to see whether it’s safe to give it to your pet. You should always consult the vet before you decide to put your dog on supplements.
  • Compatibility with other medication. If you’re dog is already on some supplement or medication, you need to check with the vet whether your dog can safely take both the glucosamine and the medication or vitamins they’re already using. If you’re dog is in need of different vitamins and nutrients, take a look at our list of the best dog multivitamins.
  • Different forms. Glucosamine supplements come in the form of liquid, powder, chewable tablets or chew treats. Think about the easiest way to administer your dog a supplement, whether it’s in liquid or solid form. Many glucosamine chew treats come with a flavor, so if your dog is a picky eater, it’s a good idea to think about their favorite flavors before you purchase glucosamine. 

Frequently Asked Questions

What is glucosamine for dogs and how does it work?

Glucosamine supplements for dogs are formulated to help reduce the pain and stiffness caused by joint and hip problems. The substance is either naturally extracted from the shells of crabs, oysters, and shrimp or synthesized in labs from plant sources. Glucosamine helps repair damaged cartilage cells and it improves mobility and flexibility in aging dogs. Including glucosamine supplements in your dog’s diet can help them move around easier and can make activities such as going for a walk or going up the stairs more comfortable and pain-free. If you need more information on supplements that promote joint health, take a look at our list of the best joint supplements for dogs

How much glucosamine should you give a dog?

Glucosamine products come with an instruction on the right dosage for your pet depending on their weight. However, you should always consult the vet prior to giving supplements to your dog. The vet will have a better insight into your dog’s condition and they can determine the optimal dosage and schedule for your pet. 

What are the side effects of glucosamine for dogs?

The side effects of glucosamine for dogs are generally rare and mild. In some cases, they included fatigue, insomnia, and excessive thirst and urination, the last one occurring when the supplement is administered in high dosage. There is also a risk of allergic reaction, since glucosamine is naturally extracted from the shells of crabs, oysters, and shrimp, so you should be careful if your dog is allergic to shellfish. Also, since glucosamine is a sugar-based substance, it may not be suitable for dogs with diabetes. If you notice any symptoms that are concerning, immediately turn to your vet.

How long does it take for glucosamine to work in dogs?

Every dog is different, but it usually takes weeks before you can see any improvement. Vets suggest that effects of the glucosamine can be observed after 3 months of usage. 

Other Glucosamine Supplements We Reviewed

Top pick
Nutramax Cosequin DS Plus with MSM Chewable Tablets

Nutramax Cosequin gets your aging dog back on their feet with its powerful formula that improves motion and reduces pain.

Check Price

We looked at 20 other glucosamine supplements for dogs. Even though they didn’t make our 5 best list, they’re the best of the rest and each is still a great option for your pet. The information you’ll need to compare each one is included with the listing.

Glucosamine Tablets

Infinite Pet Supplements All-Natural Hip & Joint Supplement for Dogs

Infinite Pet Supplements All-Natural Hip and Joint Supplements

This product contains glucosamine, chondroitin, MSM, and organic turmeric to support and repair joints and cartilage and to help retain flexibility. 

Key Features

  • Glucosamine, chondroitin, MSM, and organic turmeric
  • Human-grade ingredients
  • Beef liver flavor
  • 90 tablets
  • Lifetime money-back guarantee
  • Made in the USA

Cost: $30

Lloyd and Lucy’s Pet Supplies Best Value Glucosamine for Dogs

Lloyd and Lucy's Best Value Glucosamine for Dogs

This glucosamine supplement is formulated with glucosamine, chondroitin, MSM, Vitamin C, and manganese to support your dog’s joint mobility.

Key Features

  • Formulated with glucosamine, chondroitin, MSM, Vitamin C, and manganese
  • Liver flavor
  • 180 chewable tablets
  • Money-back guarantee

Cost: $35

Nutramax Dasuquin with MSM Chewables

Nutramax Dasuquin with MSM Chewables

This glucosamine is formulated with chondroitin sulfate and MSM to help support cartilage matrix production and joint comfort. 

Key Features

  • Formulated with chondroitin sulfate and MSM
  • 150 counts
  • Formulated from more than 10 years of clinical use and research
  • Ideal for dogs over 60 pounds

Cost: $75

Glucosamine Chews

Active Chews Premium Hip and Joint Dog Treats

Active Chews Premium Hip and Joint Dog Treats

Active Chews glucosamine is formulated with glucosamine, chondroitin, MSM, organic turmeric, and organic black pepper to boost mobility and overall joint health in your dog’s senior years. 

Key Features

  • Formulated with glucosamine, chondroitin, MSM, organic turmeric, and organic black pepper
  • No heat no cook process
  • Chicken flavor
  • 120 soft chews
  • 30-day money-back guarantee
  • Made in the USA

Cost: $25

ActivFlex – Glucosamine for Dogs

ActivFlex Glucosamine for Dogs

ActivFlex features a formula made of glucosamine, chondroitin, MSM, yucca schidigera, and Vitamin C and E to reduce inflammation and help with the treatment of arthritis symptoms. 

Key Features

  • Glucosamine, chondroitin, MSM, yucca schidigera, and Vitamin C and E
  • Grain-free
  • Chicken flavor
  • 120 soft chews
  • Money-back guarantee

Cost: $30

Bayer Synovi G4 Soft Chews for Dogs

Bayer Synovi G4 Soft Chews for Dogs

This glucosamine supplement features a powerful combination of ingredients that assists with joint health, muscle tone and antioxidant function. 

Key Features

  • Formulated with glucosamine, chondroitin, MSM, green-lipped mussel, and manganese
  • Creatine supports muscle tone and contraction
  • Vitamin C, turmeric, Vitamin E, grape seed extract, and selenium remove free radicals
  • 120 soft chews
  • National Animal Supplement Council Quality Seal

Cost: $46

Joint Max Triple Strength Glucosamine for Dogs

Joint Max Triple Strength Glucosamine for Dogs

This supplement contains powerful active ingredients that enhance the functions of joint and connective tissue as well as antioxidants to help reduce oxidative stress. It features glucosamine, chondroitin, zinc, and Vitamin C.

Key Features

  • Formulated with glucosamine, chondroitin, MSM, creatine, and hyaluronic acid 
  • Vitamin C, Vitamin E, and zinc help reduce free radicals and oxidative stress
  • 240 soft chews
  • Can be used with prescription drugs

Cost: $52

NaturVet Glucosamine DS Plus Level 2 Moderate

NaturVet Glucosamine DS Plus Level 2 Moderate

Gucosamine supplement by NaturVet contains glucosamine, MSM, and chondroitin together with antioxidants to help support the structural integrity of joints and connective tissues. It also helps alleviate your dog’s aches and discomfort associated with daily exercise.

Key Features

  • Formulated with glucosamine, MSM, and chondroitin
  • Great for large breeds and overweight dogs
  • Safe for all dogs over the age of 12 weeks
  • 120 soft chews
  • Made in the USA

Cost: $25

Nootie Glucosamine Chondroitin for Dogs

Nootie Glucosamine Chondroitin for Dogs

This glucosamine product is formulated with chondroitin, turmeric, and hyaluronic acid to reduce inflammation and joint pain. 

Key Features

  • Formulated with chondroitin, turmeric, and hyaluronic acid
  • 250 soft chews
  • Made in the USA

Cost: $33

Paws & Pals Glucosamine Supplement for Dogs

Paws & Pals Glucosamine Supplement for Dogs

Glucosamine by Paws & Pals features a formula with a blend of vitamins, minerals, antioxidants, plants, and nutrients to improve mobility and reduce joint pain.

Key Features

  • Formulated with chondroitin, MSM, flaxseed, rosemary, and fish oil
  • 240 soft chews
  • Made in the USA

Cost: $27

Pet Blue Naturals Glucosamine for Dogs

Pet Blue Naturals Glucosamine for Dogs

Glucosamine by Pet Blue Naturals features chondroitin and MSM to help repair cartilage and organic turmeric to reduce inflammation and free radicals.

Key Features

  • Formulated with glucosamine, chondroitin, MSM, and organic turmeric
  • Vitamin C and E for preventative care
  • No corn, wheat, soy, dairy or gluten
  • Bacon flavor
  • 90 soft chews

Cost: $34

POINTPET Advanced Hip and Joint Supplement for Dogs

POINTPET Advanced Hip and Joint Supplement for Dogs

This glucosamine supplement is formulated with organic ground hemp and hemp seed oil to improve mobility and reduce pain and inflammation. 

Key Features

  • Formulated with glucosamine, chondroitin, MSM
  • Vitamin E, Omega-3 and Omega-6 fatty acids for extra health benefits
  • Made without corn, wheat, soy or gluten
  • Duck flavor
  • 90 soft chews
  • 30-day money-back guarantee

Cost: $35

Rocco & Roxie Glucosamine for Dogs

Rocco & Roxie Glucosamine for Dogs

This glucosamine supplement features a powerful blend of ingredients including glucosamine, chondroitin, MSM, tart cherry, and curcumin to soothe inflammation, provide pain relief from arthritis, and maintain overall mobility.

Key Features

  • Glucosamine, chondroitin, and MSM for joint support
  • Tart cherry and curcumin for anti-inflammatory effect
  • Duck flavor
  • No binders, fillers, gums, starch or sweeteners
  • Processed at low temperatures to preserve nutrient integrity
  • 120 soft chews
  • Made in the USA
  • Money-back guarantee

Cost: $35

VetriScience Laboratories – GlycoFlex 3 Hip and Joint Support for Dogs

VetriScience Laboratories - GlycoFlex 3 Hip and Joint Support for Dogs

Glucosamine by VetriScience is recommended for working dog breeds, very active dogs and senior dogs showing signs of joint health problems.

Key Features

  • Contains glucosamine, chondroitin, and MSM
  • Green –lipped mussel helps repair cartilage
  • Proven to increase hind leg strength in dogs by up to 41% in 4 weeks
  • Chicken liver or duck flavor
  • 120 soft chews

Cost: $46

Liquid Glucosamine

Grizzly Pet Products Liquid Hip & Joint Product

Grizzly Pet Products Grizzly Joint Health Liquid Hip & Joint Product

This glucosamine supplement helps maintain the health of hips, joints, cartilage, collagen, and other cell structures of the body that are responsible for movement. 

Key Features

  • Formulated with glucosamine, chondroitin, MSM, turmeric, krill oil, and hyaluronic acid
  • Krill oil supports digestive absorption
  • Certified by the National Animal Supplement Council
  • 32 oz.

Cost: $20

Liquid Health K-9 Glucosamine Hip and Joint Formula

Liquid Health K-9 Glucosamine

Glucosamine by Liquid Health features a formula that aids in the prevention of arthritis in younger dogs. 

Key Features

  • Formulated with glucosamine, chondroitin, and MSM
  • Certified by the National Animal Supplement Council
  • 32 oz
  • Made in the USA

Cost: $28

Glucosamine Powder

Extend Joint Care Natural Glucosamine with MSM for Dogs

Extend Joint Care Natural Glucosamine with MSM for Dogs

Glucosamine by Extend Pets contains MSM and ascorbic acid that increases the production of collagen. 

Key Features

  • Formulated with glucosamine, MSM and ascorbic acid
  • Beef flavor
  • Natural ingredients
  • 2 boxes (30 powder packets per box)
  • Life time money-back guarantee

Cost: $80

Infinite Pet Supplements All-Natural Hip & Joint Supplement for Dogs

Infinite Pet Supplements All-Natural Hip & Joint Supplement for Dogs

This glucosamine supplement now also comes in the form of powder with the same formula of powerful ingredients including glucosamine, chondroitin, MSM, and turmeric. 

Key Features

  • Formulated with glucosamine, chondroitin, MSM, and turmeric
  • No additives, fillers or artificial flavors
  • Made in the USA
  • Lifetime money-back guarantee

Cost: $30

Nature’s Pure Edge Hip and Joint with Turmeric

Nature's Pure Edge Hip and Joint with Turmeric

This glucosamine supplement features turmeric to reduce inflammation, strengthen the immune system, and provide vitamins for the skin and coat. It’s suitable for cats and dogs. 

Key Features:

  • Contains glucosamine, chondroitin, MSM, turmeric, and organic sea coral calcium
  • Made in the USA
  • Money-back guarantee

Cost: $20

NuLife Natural Pet Health Advanced Hip and Joint Supplement for Dogs

NuLife Natural Pet Health Advanced Hip and Joint Supplement for Dogs

This glucosamine supplement features a formula that helps repair cartilage, alleviate joint pain, and strengthen the immune system. 

Key Features

  • Formulated with glucosamine, chondroitin, MSM, and organic coral calcium
  • Organic coral calcium contains more than 74 naturally occurring trace minerals that strengthen the immune system
  • 6 oz.
  • Lasts up to 72 days
  • Made in the USA

Cost: $25

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