The Best Dog Digestive Enzymes

Digestive enzymes help dogs break down their food and absorb its nutrients. They are produced naturally by the body, but many dogs can benefit from digestive enzyme supplementation. Dog digestive enzymes are available in powder, soft chew, and capsule form. Some products also contain other supplements such as vitamins and probiotics to support your dog’s health. Dog digestive enzymes are particularly beneficial for older pets and those with acute health conditions which prevent their bodies from producing sufficient enzymes.

We reviewed dozens of dog digestive enzymes to identify the best of the best, based on factors including quality, affordability, and Amazon reviews. We then narrowed down our search to 5 of the top-rated dog digestive enzymes available today.

Top Pick
PetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes

A complete digestive health and immune system booster with 20 active ingredients.

$19.95 USD

During the course of our research we identified PetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes as the best dog digestive enzymes. The tasty chews have 20 active ingredients to support digestive health, boost immune system function, and improve your dog’s overall health and vitality.

The 5 Top-Rated Dog Digestive Enzymes for 2019

Editor's PicksBrandRating
Best OverallPetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes4.4
Runner UpZesty Paws Advanced Multivitamin for Dogs4.7
Best Budget BuyNaturVet Digestive Enzymes Plus Probiotic4.3
Best Dog Digestive Enzyme PowderNUSENTIA Enzymes for Dogs & Cats4.1
Best Dog Digestive Enzyme ChewsZesty Paws Probiotic for Dogs with Natural Digestive Enzymes4.7

*Ratings are from Amazon at the time of publication and can change

Our Top Pick: PetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes

PetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes are formulated with premium ingredients to support your dog’s digestive health. The soft, tasty chews perform a range of important functions in your dog’s body, including boosting the immune system and promoting absorption of vital nutrients.

This popular and well-reviewed product is perfect for preventing issues such as diarrhea, constipation, malabsorption, and yeast infection. It is also suitable for dogs with skin conditions and other illnesses caused by immune imbalances.

PetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes Key Features: 

  • Complete digestive health and immune system booster
  • Helps protect against infection and disease
  • 20 active ingredients
  • Healthy and tasty soft chews

Our Runner Up Pick: Zesty Paws Advanced Multivitamin for Dogs

Runner Up
Zesty Paws Advanced Multivitamin for Dogs

5-in-1 multivitamin bites with digestive enzymes and probiotics.

$37.97 USD

If you’re looking for a dog multivitamin with digestive enzymes, look no further than Zesty Paws Advanced Multivitamin for Dogs. The 5-in-1 formula provides support for the skin, coat, joints, heart, digestive function, and immune response.

The tasty chews contain over 35 vitamins, minerals, and nutrients that provide daily nutritional support for dogs of all ages. Reviewers say the product is effective and the flavors are popular with their dogs.

Zesty Paws Advanced Multivitamin for Dogs Key Features: 

  • Advanced 5-in-1 formula supports your dog’s overall health
  • Contains powerful digestive enzymes
  • Over 35 vitamins, minerals, and nutrients
  • Suitable for dogs of all ages

Best Budget Pick: NaturVet Digestive Enzymes Plus Probiotic

Best for Budget
NaturVet Digestive Enzymes Plus Probiotic

Effective and affordable dog digestive enzymes with added probiotics.

$21.75 USD

NaturVet Digestive Enzymes Plus Probiotic is formulated to help your pet break down food for optimal utilization of nutrients.  The affordably-priced powder contains digestive enzymes including alpha-Amylase, protease, cellulase, and lipase.

The veterinarian formulated powder is suitable for cats and dogs, and comes with a 100% satisfaction guarantee. Reviewers say the product is effective, well-priced, and long-lasting.

NaturVet Digestive Enzymes Plus Probiotic Key Features: 

  • Provides probiotics and essential enzymes
  • Veterinarian formulated
  • Suitable for cats and dogs
  • 100% satisfaction guarantee

Best Dog Digestive Enzyme Powder: NUSENTIA Enzymes for Dogs & Cats

Best Dog Digestive Enzyme Powder
NUSENTIA Enzymes for Dogs & Cats

A 100% natural powder with 11 types of plant-based systemic and digestive enzymes.

$38.58 USD

If you’re looking for a an effective and natural dog digestive enzyme powder, NUSENTIA Enzymes for Dogs & Cats is an excellent choice. The great-tasting, convenient powder contains 11 types of plant-based and systemic digestive enzymes that help keep your pet’s digestive system running smoothly.

This product is suitable for cats and dogs with health problems including indigestion, toxin-buildup, and yeast issues. Just one economical scoop per day supports complete nutrient absorption for great health.

NUSENTIA Enzymes for Dogs & Cats Key Features: 

  • Contains 11 types of plant-based and systemic digestive enzymes
  • Supports complete nutrient absorption
  • Suitable for cats and dogs
  • Veterinarian recommended
  • 364 servings

Best Dog Digestive Enzyme Chews: Zesty Paws Probiotic for Dogs with Natural Digestive Enzymes

Best Dog Digestive Enzyme Chews
Zesty Paws Probiotic for Dogs with Natural Digestive Enzymes

Pumpkin flavor soft chews loaded with natural digestive enzymes.

$25.97 USD

Zesty Paws Probiotic for Dogs with Natural Digestive Enzymes contains powerful probiotics and digestive enzymes to support digestion, immune function, and protein utilization in dogs of all ages and sizes. The flavorful chews are useful for relieving issues such as gas, bloating, constipation, and stomach discomfort.

The chews double as a healthy treat and are a great addition to any canine’s diet. Most reviewers highly recommend these probiotic bites, and say they are great for pets with sensitive stomachs.

Zesty Paws Probiotic for Dogs with Natural Digestive Enzymes Key Features: 

  • Contains powerful probiotics and digestive enzymes
  • Delicious pumpkin flavor bites
  • Supports digestion, immune function, and protein utilization
  • Suitable for dogs of all ages and sizes

Who Should Buy Dog Digestive Enzymes

Digestive enzymes are produced naturally by the body, and are vital for digestion and overall health. Their role is to break down food and make nutrients available for absorption. Unfortunately, many older dogs and those with digestive disorders or other health conditions do not produce an adequate amount of digestive enzymes. This can result in nutritional deficiencies that can impact a dog’s health.

Supplementation with digestive enzymes is a great solution for dogs that are unable to produce enough enzymes naturally. If your dog has digestive issues, please ask your veterinarian if dog digestive enzymes are appropriate for your pet. If your dog has a sensitive stomach, check out our review of the best organic and natural dog foods for some limited-ingredient, tummy-friendly options for your dog.

Top Pick
PetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes

A complete digestive health and immune system booster with 20 active ingredients.

$19.95 USD

Important Features to Consider

Dog digestive enzymes should have a few important features. Here’s what to consider when selecting the perfect digestive enzyme supplement for your pup:

  • Ingredients. Look for a supplement which contains natural digestive enzymes that are proven to help your dog break down food and absorb its nutrients. The four most beneficial types of digestive enzymes are protease, amylase, lipase, and cellulase. These help break down protein, carbohydrates, fat, and fiber in the body.
  • Added supplements. Many dog digestive enzyme products contain additional supplements to support your pet’s health. These include multivitamins, prebiotics, and probiotics. Digestive enzymes with added supplements can be a good solution for dogs that need additional dietary support. Please ask your veterinarian if these products are appropriate for your dog.
  • Formula. Dog digestive enzymes are available in powder, soft chew, or capsule form. We recommend choosing a product that’s both economical and easy to administer.
  • Affordability. Dog digestive enzymes usually need to be given daily. For this reason, the price of supplements can quickly add up. Consider your budget when choosing dog digestive enzymes, and aim to buy the best product within your price range.

Frequently Asked Questions

What are dog digestive enzymes and how do they work?

Dog digestive enzymes are a type of supplement that replace vital enzymes produced by the body. These enzymes help dogs break down food and absorb its nutrients. Digestive enzyme supplementation can be very beneficial for older dogs or those with health conditions which prevent their bodies from producing enough enzymes.

Are digestive enzymes the same as probiotics?

No. digestive enzymes and probiotics perform different functions in the body. Digestive enzymes are proteins which are produced in the gastrointestinal tract. Their role is to break down food into digestible nutrients. Probiotics are live microorganisms which aid overall digestive function.

How can I add digestive enzymes to my dog’s diet?

Digestive enzyme supplements can be given to your dog directly or mixed into their food. They are available in powder, soft chew, or capsule form.

How do I know if my dog needs digestive enzymes?

Symptoms of enzyme deficiency include diarrhea, bloating, gas, and other digestive issues. Please consult with your veterinarian before supplementing your dog’s diet with digestive enzymes.

Other Dog Digestive Enzymes We Reviewed

Top Pick
PetVitalityPro Probiotics for Dogs with Natural Digestive Enzymes

A complete digestive health and immune system booster with 20 active ingredients.

$19.95 USD

We looked at 20 other dog digestive enzymes that are designed to support your pet’s gastrointestinal health. Even though they didn’t make our 5 best dog digestive enzymes list, they’re the best of the rest and each is still a great option for your dog. The information you’ll need to compare each one is included with the listing.

Dog Digestive Enzyme Powder

Ample Nutrition Digestive Enzymes For Pets

Ample Nutrition Digestive Enzymes For Pets

High potency daily digestive enzymes for pets that promote optimum digestion and immune function. Reviewers say this product is perfect for pets with sensitive stomachs.

Key Features: 

  • Contains 9 high potency digestive enzymes
  • Formulated by veterinarians
  • Provides enhanced digestive support
  • Increases nutrient absorption

Cost: $24

Dr. Mercola Digestive Enzymes For Pets

Dr. Mercola Digestive Enzymes For Pets

High-quality digestive enzymes for pets from the popular Dr. Mercola brand. Reviewers say this product is excellent for soothing digestive issues.

Key Features: 

  • Contains essential digestive enzymes
  • Promotes the absorption of essential nutrients
  • Manufactured under high quality standards to help ensure purity
  • Suitable for dogs and cats

Cost: $20

In Clover Optagest Organic Prebiotic Natural Enzyme Powder

In Clover Optagest Organic Prebiotic Natural Enzyme Powder

This fast-working, premium natural enzyme powder from Optagest contains four plant-based enzymes that promote digestive health.

Key Features: 

  • Scientifically formulated
  • Contains four plant-based enzymes
  • Human-grade ingredients
  • Promotes a healthy intestinal balance
  • Available in 3 sizes

Cost: $9-$46

NUSENTIA Enzyme Miracle

NUSENTIA Enzyme Miracle

This popular product from NUSENTIA contains 11 types of plant-based systemic and digestive enzymes to support your pet’s health.

Key Features: 

  • Plant-based enzymes combat systemic and digestive stress
  • 100% safe and natural
  • Money back guarantee
  • 100 servings

Cost: $24

NWC Naturals Total-Zymes Digestive Powder

NWC Naturals Total-Zymes Digestive Powder

This digestive enzyme powder from NWC Naturals is recommended by veterinarians and contains 16 powerful enzymes for complete digestion.

Key Features: 

  • Contains 16 powerful enzymes
  • Helps support digestion and prevent common health issues
  • No artificial colors, flavors, or preservatives
  • 2 sizes available

Cost: $19-$24

Pan-tenex 10x Digestive Enzymes for Dogs

Pan-tenex 10x Digestive Enzymes for Dogs

This high potency amylase, protease, and lipase digestive enzyme concentrate is designed to support proper digestive activity in dogs.

Key Features: 

  • High potency formula
  • Assists your dog’s natural digestive process
  • Suitable for dogs with digestive issues

Cost: $52

Pure Paw Nutrition Probiotics for Dogs & Cats with Prebiotics & Digestive Enzymes

Pure Paw Nutrition Probiotics for Dogs & Cats with Prebiotics & Digestive Enzymes

A high-quality probiotic, prebiotic, and digestive enzyme blend for pets that detoxifies and nourishes the digestive tract.

Key Features: 

  • Formulated for large cats and dogs
  • Detoxifies and nourishes the digestive tract
  • Flavored with real beef liver
  • Easy to mix into food
  • 2 sizes available

Cost: $25-$40

Wholistic Pet Organics Digest-All Plus Supplement

Wholistic Pet Organics Digest-All Plus Supplement

An advanced, concentrated formula of digestive enzymes and powerful probiotics that provides superior digestive health for pets.

Key Features: 

  • Designed to maximize digestion of proteins, starches, and carbohydrates
  • Contains natural whole ingredients
  • Concentrated formula of digestive enzymes and probiotics
  • Made in the USA
  • 3 sizes to choose from

Cost: $14-$33

Dog Digestive Enzyme Chews

Active Chews Premium Probiotics for Dogs with Digestive Enzymes

Active Chews Premium Probiotics for Dogs with Digestive Enzymes

Natural duck flavored soft chews with all-natural active ingredients including probiotics and high potency digestive enzymes.

Key Features: 

  • Improves digestive function and boosts the immune system
  • All-natural ingredients
  • Tasty duck flavor treats
  • 100% money back guarantee

Cost: $20

Buddy&Max Probiotic Chews for Dogs with Digestive Enzymes

Buddy&Max Probiotic Chews for Dogs with Digestive Enzymes

Highly effective, natural, and organic soft chews with a blend of powerful digestive enzymes, prebiotics, and probiotics.

Key Features: 

  • Natural and organic
  • No artificial preservatives or fillers
  • Balanced probiotic and digestive enzyme formula
  • Suitable for daily use

Cost: $27

Deley Naturals Grain Free Probiotics for Dogs

Deley Naturals Grain Free Probiotics for Dogs

This advanced probiotic supplement for dogs from Deley Naturals contains a blend of 6 essential digestive enzymes that improve digestion and nutrient absorption.

Key Features: 

  • Restores digestive health and boosts the immune system
  • Contains 6 essential dog digestive enzymes
  • Natural chicken flavor chews
  • Safe, easy, and convenient

Cost: $27

NaturVet Advanced Probiotics & Enzymes

NaturVet Advanced Probiotics & Enzymes

Soft chews with digestive enzymes and vet strength PB6 probiotic for optimal stomach and intestinal health. Reviewers say these chews work quickly and effectively.

Key Features: 

  • Supports and balances your dog’s gastrointestinal environment
  • Contains digestive enzymes and vet strength PB6 probiotic
  • Wheat free formula
  • 100% money back guarantee
  • 2 sizes available

Cost: $15-$24

NaturVet Digestive Enzymes Plus Probiotic for Dogs Soft Chews

NaturVet Digestive Enzymes Plus Probiotic for Dogs Soft Chews

A veterinarian formulated digestive enzyme supplement that provides a healthy level of probiotics and essential enzymes to help your dog break down food.

Key Features: 

  • Veterinarian formulated
  • Helps your dog break down food and absorb nutrients
  • Soft, tasty chews
  • 100% money back guarantee
  • Several sizes to choose from

Cost: $13-$46

PawParents Dog Probiotics Chewable Natural Digestive Enzymes

PawParents Dog Probiotics Chewable Natural Digestive Enzymes

These soft chews from PawParents are formulated with a perfectly balanced blend of probiotics, prebiotics, and digestive enzymes.

Key Features: 

  • Restores gut health and strengthens your dog’s immune system
  • Balanced blend of probiotics, prebiotics, and digestive enzymes
  • Free from unhealthy fillers
  • Guaranteed quality

Cost: $18

Paws & Pals Dog Digestive Enzymes Plus Probiotics

Paws & Pals Dog Digestive Enzymes Plus Probiotics

Tasty, chewable digestive enzymes from Paws & Pals with hearty, natural ingredients including papaya to promote digestive health.

Key Features: 

  • High in fiber
  • Aids nutrient absorption
  • Alleviates digestive conditions such as bloating, diarrhea, and indigestion
  • Contains natural ingredients

Cost: $17

Power to Your Pet Digestive Defense

Power to Your Pet Digestive Defense

3-in-1 soft chews with prebiotics, probiotics, and digestive enzymes for complete digestive support. These convenient chews help eliminate problems such as gas, diarrhea, and bad breath.

Key Features: 

  • Tasty 3-in-1 chews
  • Contains prebiotics, probiotics, and digestive enzymes
  • Promotes healthy digestion
  • Convenient and easy to use

Cost: $25

Tummy Treats Probiotics for Dogs

Tummy Treats Probiotics for Dogs

Safe, effective probiotics for dogs with a proprietary digestive enzyme blend. These chews are all-natural with no dairy, sugars, salts, or gumming agents.

Key Features: 

  • Safe, all-natural ingredients
  • Grain, wheat, soy, and corn free
  • Optimizes your dog’s digestion
  • 100% lifetime satisfaction guarantee

Cost: $28

Vita Pet Life Probiotics for Dogs and Enzymes

Vita Pet Life Probiotics for Dogs and Enzymes

Chewable tablets from a brand you can trust that support healthy digestion, immune function, and nutrient absorption.

Key Features: 

  • Contains probiotics and digestive enzymes
  • Effective for treatment of diarrhea and other digestive issues
  • High-quality ingredients
  • 100% satisfaction guaranteed

Cost: $18

Dog Digestive Enzyme Capsules

Azmira Digest Zymez

Azmira Digest Zymez

Digestive enzyme capsules that are designed to increase nutrient assimilation and improve digestive health in dogs.

Key Features: 

  • Supports pancreatic problems and irritable bowel syndrome
  • Increases nutrient assimilation, especially for raw meat eaters
  • Can be fed orally or opened and mixed into food
  • Designed for meat eating pets

Cost: $26

The Canine Couch California Dog Probiotic

The Canine Couch California Dog Probiotic

An all-natural dog supplement that contains a healthy digestive enzyme blend. Reviewers say these capsules are effective at stabilizing digestion.

Key Features: 

  • Promotes immune function and digestive health
  • Easy-open capsules
  • Safe, high-quality ingredients
  • Alleviates digestive issues

Cost: $26

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