The Best Dog Anxiety Medication

Dogs experience anxiety issues for many reasons, sometimes behavioral and sometimes situational. No matter the cause, there are some steps you can take to help ensure your pet does not suffer with this unpleasant feeling, and anxiety, calming medications are one solution.

Finding the best dog anxiety medication for your pooch means reading reviews, studying product features, and diving into the ins and outs of ingredients and delivery options. With the right dog anxiety medication, your nervous pooch can become a calm, happy and healthy pup. We reviewed dozens of dog anxiety medications and calming treats to identify the best of the best, based on Amazon reviews, how well they performed in testing, cost, and other considerations. We narrowed our search down to 5 of the top-rated dog anxiety meds pet owners can purchase to ensure a calm and happy pooch.

Top Pick

The Anxious Pet Calming Soft Chews with CBD

These tasty CBD chews will help to reduce stress and anxiety in your pooch.

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We’ve identified The Anxious Pet Calming Soft Chews with CBD as the best dog anxiety, calming medication out there. With its natural ingredients and multi-functional formula, this dog anxiety medication is one that will keep your pooch feeling happy and calm. These benefits allow your dog to live their best life, and you to rest easy knowing they aren’t overly stressed out.

The 5 Top-Rated Dog Anxiety, Calming Medications

Editor’s PicksBrandRating
Best OverallThe Anxious Pet Calming Soft Chews with CBD4.9
Best CBD Oil for Dog AnxietyCBDFX Pet CBD Oil 600mg (Large Breed)4.9
Best Budget BuyNutri-Vet Pet-Ease Soft Chews4.0
Best Hemp-Based Dog Anxiety TreatJoy Organics Premium CBD Dogs Treats4.5
Best Natural Dog Anxiety MedicationReady Pet Go! Natural Calming Treats for Dogs4.6

*Ratings are from Amazon at the time of publication and can change

Our Top Pick: The Anxious Pet Calming Soft Chews with CBD

Are you looking for reliable, natural way to calm your anxious or stressed dog down? The Anxious Pet Calming Soft Chews with CBD is our top pick for the job. These dog-friendly chew treats are veterinarian formulated and 3rd party tested to ensure your dog gets the relief they need, safely. They come in two tasty flavors (peanut butter or bacon flavor), and are completely vegan and grain-free.

The Anxious Pet Calming Soft Chews with CBD are made with an effective blend of naturally calming ingredients. The 5 mg of organic CBD included in each chew is no doubt the starring ingredient in the formulation. CBD is not only well-known for its calming, anxiety-reducing properties, but also its ability to help reduce inflammation. Other key ingredients in these chew include TAP10 (a proprietary blend of acetyl L- carnitine, magnolia, St. John’s wart, and barberry), organic Flaxseed, and organic MCT oil.

Interested in giving this natural anxiety medicine a go? You can get a tub of 90 chews for the reasonable price of $48. US customers can also enjoy free and fast shipping, as well as contactless delivery. If you still need a bit more convincing, keep in mind that you can try these chews for 60 days, and if you’re 100% satisfied with them, The Anxious Pet will provide you with a full refund. 

The Anxious Pet Calming Soft Chews with CBD Key Features:

  • 5 mg of organic CBD per chew
  • 3rd party tested
  • Free, fast shipping (US customers only) and a money-back satisfaction guarantee

Best CBD Oil for Dog Anxiety: CBDfx CBD Oil For Small Dogs and Cats

Best CBD Oil for Dog Anxiety

CBDfx Pet CBD Oil 600mg (Large Breed)

This organinc CBD oil can help to dampen your dog’s anxiety levels.

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CBDfx Pet CBD Oil 600mg (Large Breed) took the second place spot on our list of the best dog anxiety medications for a variety of reasons. To begin with, it’s a completely natural, drug-free way to treat your dog’s anxiety. While there are many different CBD oil products for dogs on the market, we believe this one is a top choice for calming anxious dogs because it’s 100% organic and third-party tested for potency and purity. Moreover, it’s free of GMOs, additives, solvents, and chemicals.

Another reason we believe that this CBD oil is such a great choice is that it can also be used to help address a range of other health problems your dog may be experiencing. For example, sore joints, nausea, and pain. It also boasts strong customer reviews. Those who purchased and reviewed it not only appreciated that it helped with their dogs’ anxiety levels, but also that their dogs genuinely liked taking it. 

At a cost of around $70 for a 30mL bottle, it doesn’t come cheap. That said, the quality of the ingredients used in production and the brand recognition for safety more than justifies that price. With 600mg of CBD per bottle, it also contains a relatively high amount of CBD—of which is organic—so the price is in actual fact quite reasonable. Just keep in mind that this level of CBD potency means that this particular product is only suitable for large dog breeds. Those with smaller dogs should opt for the CBDfx CBD Oil For Dogs and Cats 150mg (Small Breeds) instead.

CBDfx Pet CBD Oil 600mg (Large Breed) Key Features:

  • Third-party tested CBD
  • Organic formula
  • 30-day money back guarantee

Best Budget Pick: Nutri-Vet Pet-Ease Soft Chews

Best for Budget

Nutri-Vet Pet-Ease Soft Chews

A budget-friendly option packed tasty, high-quality natural ingredients

Nutri-Vet Pet-Ease Soft Chews are an excellent choice for those looking for a dog anxiety medication that won’t break the bank. Each packet contains 70 soft chews that are made with chamomile and tryptophan to soothe your dog’s anxiety naturally. These veterinary-formulated soft chews are suitable for dogs of all sizes and have a tasty natural hickory smoke flavor your dog is sure to look forward to each time. 

Most dog owners who purchased and reviewed this dog anxiety medication expressed their relief that they actually work! Just have a peek at the reviews yourself to see that dog owners have commented that they “worked wonders” and “work like a charm”. One even called them “life changing.”

With a price tag of only $3/70 soft chews, this dog anxiety medication is unbelievably affordable. It’s a solid choice for those looking for a dog anxiety medication option on a budget. It has a rating of 4.0 on Amazon, which shows that this budget-friendly pick is just as good at calming their pooch as more expensive options.

Nutri-Vet Pet-Ease Soft Chews Key Features:

  • Natural hickory smoke flavor
  • For dogs of all sizes
  • 70 count

Best Hemp-Based Dog Anxiety Treats: Joy Organics Premium CBD Dogs Treats

Best Hemp-Based Dog Anxiety Treats

Joy Organics Premium CBD Dog Treats

Made from organic ingredients with a natural flavor dogs love.

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Joy Organics Premium CBD Dog Treats are made with organic sweet potato, sunflower, vitamin e, and hemp to help provide your canine companion with a sense of calm. They feature a natural beef flavor that dogs love, and are given as a soft chew — making them easy for dogs of all ages and sizes to take.

There were a few customers who said the Joy Organics customer service was outstanding in taking care of their needs. Joy Organics is a family founded company that’s managed by Joy’s family.

At a cost of around $35/30 chews, it’s quite affordable as far as the cost of dog anxiety medication goes, and the quality ingredients, as well as the ease of feeding, more than justifies that price. It has a rating of 4.5 stars, which we think goes a long way in convincing pet owners to make the investment.

Joy Organics Premium CBD Dog Treats Key Features:

  • Ideal for separation anxiety, weather-related woes, or other types of nervous behavior
  • Beef flavored
  • Money-back guarantee

Best Natural Dog Anxiety Medication: Ready Pet Go! Natural Calming Treats for Dogs

Best Natural Dog Anxiety Medication

Ready Pet Go! Natural Calming Treats for Dogs

All-natural ingredients and a tasty bacon and cheese flavor make this natural option a must-buy for dogs suffering from anxiety

Ready Pet Go! Natural Calming Treats for Dogs is our recommended pick if you’re looking for a dog anxiety medication that is made with natural ingredients your dog won’t turn those nose up at. The ingredient list of these USA-made chews includes thiamine and chamomile, as well as essential amino acids and soothing herbs. And how could we not mention its scrumptious bacon and cheese flavor? 

Ready Pet Go!’s chews are ideal to give your four-legged friend whenever they’re experiencing a stressful situation, such as storms of vet visits. Those who purchased and reviewed this dog anxiety medication appreciated that it helped to calm their dogs even when nothing else helped. 

With a price tag of around $26/90 chews, it’s quite an affordable option. It has a rating of 4.6 on Amazon with more than 400 people reviewing it. Be sure to give it a try if you want to provide your dog with a natural dose of relief from their anxiety. 

Ready Pet Go! Natural Calming Treats for Dogs Key Features:

  • 90 chews
  • Natural ingredients including amino acids
  • Delicious bacon and cheese flavor

Who Should Buy a Dog Anxiety Medication

A dog anxiety, calming medication is an ideal choice for those who own a dog that becomes anxious or upset to the point that it is affecting their daily living. A stressed out dog is not a happy dog, and by giving them a small amount of anxiety medication, you can make them much more comfortable. Some dogs are naturally more anxious than others, while some only experience anxiety during high-stress situations such as trips to the vet, thunderstorms, or being left alone for extended periods of time.

While the best dog anxiety medications are given as a prescription from your vet, the supplements in this article contain a blend of less potent ingredients that many pet owners find helpful in calming their pets. Always consult with your veterinarian before giving your pet something new. If you want to avoid medication or you find that medication alone isn’t enough, a dog anxiety vest is another option. Check out our review of the best dog anxiety vests to find the right one for your pup.

Top Pick

The Anxious Pet Calming Soft Chews with CBD

These tasty CBD chews will help to reduce stress and anxiety in your pooch.

Check Price

Important Features to Consider

Not all dog anxiety medications are created equal. A dog anxiety medication should calm your pet without any harmful or irritating side effects. Here’s what to consider when evaluating the options in search of the best anxiety medication for your dog:

  • Ingredients. Look for supplements that contain natural ingredients and those that have been scientifically-proven to help with calming anxiety. Things like valerian, chamomile, and L-tryptophan are all solid ingredients.
  • Formula. Some dog anxiety medications come as capsules, others are given as a soft chew, while others still are liquids that can be directly administered or mixed in with your pet’s food.
  • Size. depending on which product you choose, there will be options when it comes to how many chews or capsules are included, or how much liquid is given. If you have a larger pooch and the medication is dosed by weight, you will want a larger bottle than someone who has a small dog.
  • Price point. Finally, consider how much you are willing to spend on a dog anxiety medication. Dog anxiety medications vary in price from around $20-$50 or more. Keep an eye out for manufacturer’s coupons that can make buying dog anxiety medication more affordable.

Frequently Asked Questions

What is dog anxiety calming medication and how does it work?

Dog anxiety medication is a medication or supplement that can be given to dogs in order to help with the symptoms of anxiety. It helps to calm and relax your pet so that they can feel relaxed and calm.

What is hemp oil and is it safe for dogs?

Hemp oil is an oil derived from the hemp plant. It is known to have a variety of health benefits, including calming anxiety. While hemp is a type of cannabis plant, it does not contain the psychoactive properties of THC, which is what causes the stereotypical “high” feeling. Hemp is high in a substance called cannabidiol (CBD) which is helpful in treating anxiety in both pets and humans alike. Hemp oil is safe for dogs to consume.

What are the signs of anxiety in dogs?

The signs of anxiety in dogs can include panting, shaking, excessive barking or howling, and aggression. Anxiety can even manifest itself as destructive behaviors, such as chewing, excessive pawing or licking, and soiling where your pet knows they shouldn’t.

Can I give my dog Benadryl for anxiety?

While you can give your dog Benadryl for anxiety, it’s always best to consult with your veterinarian before doing so. The active ingredient in Benadryl, called diphenhydramine, is safe for dogs to ingest, unlike many other cold, sinus, and antihistamine drugs. The medicine helps to make them a little sleepy, which in turn can help calm anxieties.